The Mariana Trench is the deepest point on Earth

The poisonous phogo fish

The poisonous phogo fish
What are fugu fish?
Let's get to know these deadly fish, which despite their toxicity are very much loved by the Japanese, belong to the Tetraodontidae. This type of fish is slow to move, making it easy prey for other fish such as sharks, so God created them Another way to defend herself is by having a toxin called

Tetrodotoxin-TTX in his body, and a few micrograms of this poison can kill a human being or an animal!
The fugu fish is one of the most popular fish in Japan. This tasty fish contains tetrodotoxic poison, which is 1200 times more lethal than poisonous cyanide. The poison is not an antidote to healing. The poison found in one fish is enough to kill 30 people. The phantom of the fugue is found in the skin, the skeleton, the liver and the eyes, and requires the chef, who prepares it, to have the experience and the great skill to remove the poison, so that the customers are not

killed and cooked only for those who receive a government license after five years of training. Training The chef undergoes a rigorous test, where he cooks poison And deals with it.
When hunting the fish, the fisherman must carry it carefully. Before placing it in the water to go live to the restaurants, the hunter must remove its teeth, because the fugu fish fight when placed together. After cleaning the fish, the skin and the viscera containing the poison are not thrown into the garbage. Put it in tightly sealed containers to burn it, cut the fish into thin slices and eat normally raw, and the fujo fish is the only food forbidden to the Emperor of Japan to eat, because it may threaten his life.

 How does this poison work?
The mechanism of action of this toxin, tetradotoxin or TTX, depends on its superior ability to stop ionic sodium channels. It is linked to the outer hole of the ionic sodium channel, in which sodium channels are selected for transit without any other ions. This region is called the Selectivity Channel Filter).
The ionic sodium channel function stops completely when the TTX molecule binds to it and is unable to connect sodium ions from outside to the cell.

Most sodium channels have a high affinity for TTX. Thus, when connected to these channels, the electrical pulse generated by these channels is stopped. Once these channels are stopped, the muscles of the body, including the diaphragm muscles, begin to stop,  And thus death.